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To start Herblore you will need Grimy's you can obtain these by killing certain monsters or you can grow them by using Farming

To start gather some Grimy Guam's and click to clean them, this will help you start the skill because you need at least 3 Herblore to start making potions.

Next with Coins and Clean Guams in your inventory Teleport to Herblore in Skilling teleports.

Talk to Sanfew to access the ingredient shops 1 and 2

Shop 1

Shop 2

Cleaning Herbs
Herb Level Needed
Grimy guam 3
Grimy marrentill 5
Grimy tarromin 11
Grimy harralander 20
Grimy ranarr 25
Grimy toadflax 30
Grimy spirit weed 35
Grimy irit 40
Grimy avantoe 48
Grimy kwuarm 54
Grimy snapdragon 59
Grimy cadantine 65
Grimy lantadyne 67
Grimy dwarf weed 70
Grimy torstol 75

Making potions is simpler

Making Potions
Herb Ingredient Ingredient Potion Effects
Clean guam Vial of Water Eye of newt Attack Potion (3) Raises Attack level by 3
Clean marrentill Vial of Water Unicorn horn dust Antipoison (3)
Clean tarromin Vial of Water
Clean harralander Vial of Water
Clean ranarr Vial of Water
Clean toadflax Vial of Water
Clean spirit weed Vial of Water
Clean irit Vial of Water
Clean avantoe Vial of Water
Clean kwuarm Vial of Water
Clean snapdragon Vial of Water
Clean cadantine Vial of Water
Clean lantadyne Vial of Water
Clean dwarf weed Vial of Water
Clean torstol Vial of Water
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